| 1864 | Born on September 29, in Bilbao, of Basque parentage |
| 1874 | Witnessed the Carlist siege of Bilbao |
| 1875 | Started secondary education in native city |
| 1880 | Attended University of Madrid |
| 1883/84 | Graduated and acquired his doctorate. Became private teacher for a number of years |
| 1891 | Married Conceptión Lizárraga who eventually bore him 9 children. Became professor of Greek in the University of Salamanca where he will live for the rest of his life except for the years of exile. |
| 1895 | Became increasingly active as a novelist, poet and playwright |
| 1897 | Birth of son Raimundo who suffered from hydrocephalus plus meningitis. The poor child grew up retarded and died at the age of six. The tragedy of Raimundo has had a profound influence upon his father leading to his religious crisis. |
| 1900 | Elected rector of the University of Salamanca |
| 1905 | published his commentary on Cervantes Don Quixote: Lavida de Don Quijote y Sancho |
| 1910 | Published Mi religión y otros ensayos breves (My Religion and Other Short Essays). |
| 1913 | Publication of his main philosophical work: Del sentimiento trágico de la vida en los hombres y en los pueblos (On the Tragic Sense of Life in Men and in Nations) |
| 1914 | Dismissed from rectorship because of his criticism of King Alfonso XIII Remained furtheron active as a novelist and poet |
| 1924 | Because of his opposition to Premier Primo de Rivera, Unamuno was exiled to the Canary Islands (March). But in July he escaped to Paris where he stayeduntil 1930. |
| 1925 | Publication of his L'Agonie du christianisme in French (The Agony of Christianity) |
| 1930 | Rivera fell from power, Unamuno returned to Spain to join his much missed family |
| 1931 | King Alfonso abdicated. Spain was declared a republic. Unamuno re-elected as rector of the University of Salamanca |
| 1931-33 | Served as deputy to the Spanish Cortes |
| 1934 | Unamuno's wife died in May 15, followed on July 14 by the death of his married daughter Salomé. In fall, Unamuno retired from his professur and named lifetime rector of the university |
| 1936 | Outbreak of the Spanish Civil War, Unamun sided initially with General Franco's Nationalist movement. Franco's political enemy dismissed him from his rectorship. But in August, he was quickly reappointed by the Nationalist. Yet Unamuno soon quarelled with the Nationalist also and was put under house arrest until his death on December 31. |